What is Syndrome X?
A health article about Syndrome X fromYour Health Online the A to Z directory of dealing with Health Problems & nutritional Self Care Strategies
Syndrome X is a condition that occurs when patients have atypical angina chest pain, their electrocardiograms are abnormal during a stress test, but they have no signs of blocked arteries. It is more likely to occur in women.
Although it unclear what causes this condition, sensitive imaging tests are suggesting that the Syndrome may also be caused by ischemia, as is angina.
Syndrome X, also known as the "insulin resistance syndrome," may be the surest route to a heart attack. It is as powerful a predictor of coronary heart disease as elevated cholesterol or LDL "bad" cholesterol, if not more so.
Signs & Symptoms
• Insulin resistance
• Abnormalities of blood clotting
• Low HDL and high LDL cholesterol levels
• High triglyceride levels
• Central obesity (excessive fat tissue in the abdominal region)
• Impaired glucose tolerance
• High blood pressure
• Low levels of antioxidant vitamins and DHEA, with high anti-inflammatory and anti-stress hormone cortisol
If you have 3 or more of the above, you should consider yourself either having or at high risk of Syndrome X.
Can't Lose Weight? Syndrome X May Be the Culprit
With nearly 4 million Americans weighing in at over 300 pounds, is it any wonder the above cries are heard each and every day by countless frustrated people who can't lose weight? One such cause for the ever increasing need to buy larger pants is a disease known as Syndrome X.
Syndrome X is also referred to as Metabolic Syndrome, Metabolic Syndrome X and Insulin Resistance. It is a very common disease; however it is widely overlooked by many medical professionals. One statistic reveals 1 in 3 people suffer from it.
This syndrome is a precursor to developing Diabetes Type 2. Sufferers have a high level of insulin. Their bodies are unable to process all the insulin that is being made from their diet. As a result, they become insulin resistant.
Think of it like this: You knock on someone's door because you want to come in. If they don't answer, what normally happens? You knock again, right? Sometimes you may even knock a third time, trying to gain entry. Insulin works in the same manner. The pancreas produces insulin (knock). Some foods cause the body to produce even higher levels of insulin (knock again). Once you become insulin resistant, develop Syndrome X, the body is unable to properly process the glucose, therefore the pancreas tries to make up for it by producing even more insulin. It thinks "no one is home" and just keeps making more.
The main purpose of glucose is to be used as fuel for the cells in the body to produce energy. Unprocessed glucose translates into fat. If the body keeps making it and it's not being processed, where does it go? Hips, thighs, stomach, and buttocks, that's where!
In addition to hypertension and heart disease, elevated insulin may be associated with weight gain and difficulty with weight loss, other blood sugar problems such as hypoglycemia, and some menstrual related imbalances.
Genetics is partially responsible for causing this disease. More likely though is lifestyle. In many cases years of high starch, processed foods, simple sugars, lack of exercise, smoking, and increased stress may be the culprit for Metabolic Syndrome X.
Now what? For starters, start exercising today. Increase water intake and totally omit starches, sugars, processed foods from your diet. Limit or omit caffeine. Try to maintain at least one third of your daily food intake to vegetables. Ask your doctor to test your sugar levels. Change what you're eating and get walking and you'll be amazed at the pounds start to fall off. The fatigue and fuzziness will start to disappear and in turn you'll feel much better.
Types of Syndrome X
Other Diet-Related Conditions
In addition to the chronic diseases of Syndrome X, many conditions are linked with our modern diet.
Osteoporosis. Bone health requires a balance between calcium absorption and calcium excretion. This means a balance between foods that create an alkaline load in the body and those that create an acid load. Our modern diet is deficient in the fruits and vegetables we need to create an alkaline load in our bodies, and to promote our retention of the calcium we take in. The food recommended for as a source of calcium, cow’s milk, is also a food which promotes the excretion of calcium from our bones, thus negating its calcium content unless it is taken with alkaline-promoting foods. Other acid-promoting foods include grains, dairy products, animal foods, legumes, and salt.
Cancer. Elevated levels of insulin in the bloodstream as caused by high carbohydrate intake increases levels of a hormone called “insulin-like growth factor one” (IGF-1) and decreases another hormone called “insulinlike growth factor binding protein three” (IGFBP-3). The decrease in IGFBP-3 causes tissues to be less sensitive to retinoic acid, a chemical signal that normally limits tissue growth.
Increased levels of IGF-1 encourage growth. Scientists suspect that IGF-1 may be a primary promoter of unregulated and tissue growth in the body. There has been shown an association between elevated levels of IGF-1, lowered levels of IGFBP-3, and breast cancer in premenopausal women, prostate cancer in men, and colorectal cancer in all adults.
Dental Cavities. Sugar causes cavities. We hear this every time we visit the dentist. Our paleolithic ancestors consumed sugar only as it occurred naturally in fruit. Their teeth were well formed and contained virtually no cavities. Our modern diet is high in refined sugars, and many of us see our first cavities in toddlerhood.
Gluten Intolerance. Also known as Celiac’s Disease, gluten intolerance is widely underdiagnosed. It is a condition in which our bodies are unable to properly digest the grain protein, gluten. The only treatment is to eliminate all gluten-containing foods from the diet. Left untreated, gluten intolerance can lead to malnutrition and cancer. Although some suffer gluten intolerance without noticeable symptoms, others experience diarrhea, constipation, or other intestinal discomforts.
Lactose Intolerance. Unknown to many in the Western world, much of the world does not consume dairy products because of widespread intolerance to the milk sugar, lactose. Originally, our bodies were not designed to consume milk beyond the age of weaning (about four years old), and then only human milk.
What Causes Syndrome X?
The underlying cause of Syndrome X is insulin resistance - a diet-caused hormonal logjam that interferes with your body's ability to efficiently burn off the sugar you eat. The more sugar you eat, the higher the risk for syndrome X.
Syndrome X occurs when the high insulin level damages our bodies' internal systems, producing a crop of symptoms. Specifically, this group of health problems includes insulin resistance (the inability to properly deal with dietary carbohydrates and sugars), abnormal blood fats (such as elevated cholesterol and triglycerides), being overweight, and high blood pressure.
No one knows for sure what causes syndrome X. Some scientists think that a defect in specific genes may cause insulin resistance and intensive research is now underway. What we do know so far is:
• Insulin resistance is aggravated by obesity and physical inactivity; both of which are increasing in the U.S.
• The more sugar you take in, the higher the chance of you developing Syndrome X.
The fact that many obese people have high insulin levels but do not develop diabetes or syndrome X is interesting. Many obese people have high insulin sensitivity and do not have insulin resistance at all. There is evidence of a widespread variability in insulin mediated glucose disposal by muscle in non-diabetic individuals. In a study conducted by Dr.Reaven on 500 individuals, there is an apparent ten-fold difference between the most insulin sensitive and the most insulin resistant non-diabetic individual.
Cardiac syndrome X, or microvascular disease, is characterized by chest pain or ischemia without evidence of blockage in the large coronary arteries. Women are at higher risk than men for this condition.
Syndrome X may be caused when the small blood vessels in the heart don't expand enough. Postmenopausal women and women who have had surgical menopause are at risk for experiencing symptoms of syndrome X because their declining estrogen levels may affect the small blood vessels in their hearts.
Because this condition is a small vessel disease, it can't be seen on an angiogram (an x-ray with dye that identifies blockages in the blood vessels). Special imaging tests, such as PET scanning or MRI, may help with the diagnosis in the future. Today, however, syndrome X is usually a diagnosis of exclusion—meaning you may be diagnosed with this condition after tests provide no other cause for the chest pain.
Some health care professionals use the same tests used to diagnose CAD, such as an EKG, echocardiography, or coronary angiography. Many women with syndrome X have no risk factors and are otherwise healthy.
Medications commonly used to treat heart conditions may help to relieve pain caused by Syndrome X. The prognosis is generally excellent, but the symptoms can be debilitating.
Syndrome X is not an exotic disease visited on a few genetically unlucky people. Between 60 and 75 million of us are insulin resistant. A small percent of those millions, perhaps 5 to 10 percent, will develop Type 2 diabetes because their pancreases simply can't produce enough insulin to overcome the insulin resistance. The pancreases of the remaining people will furiously secrete insulin until the resistance is overcome, thus setting the stage for heart disease.
Although we haven't yet mapped out all the genes responsible for triggering Syndrome X, we do know that there must be abnormalities in several genes before the disease can manifest itself. We also know that ethnicity plays a role, with people of non-European origin being at a much greater risk.
Family history also factors into the equation, with your odds of developing Syndrome X increasing substantially if you have a family history of diseases related to insulin resistance, such as heart attack, hypertension and type 2 diabetes. Lifestyle factors are apparently as important as the genetic: improper diet, obesity, lack of physical activity and cigarette smoking worsen Syndrome X. The fact that our behaviour plays a role in the syndrome is good and bad news. We can't alter our genetic heritage, but we can change our diets and daily habits.
This deadly heart ailment begins in the bloodstream, shortly after we eat. That's not a startling idea, for we know that eating fatty or cholesterol-laden foods can be bad for our hearts. However, the Syndrome X culprit isn't red meat or butter, it's carbohydrates. Yet these carbohydrates are reluctant, inadvertent offenders.
Before entering the body proper, our food is broken down into various constituent parts in the intestine. One of these is glucose (blood sugar) from carbohydrates. Upon entering our cells, some of the glucose is put right to work providing the energy that cells need to perform their various tasks. The rest is stored in certain cells for later use. But the glucose doesn't simply flow into the storage cells. Instead, it must be guided in by insulin, a protein secreted by the pancreas.
Insulin acts like a shepherd, herding its precious flock into the cellular "corrals." Unfortunately, in many of us, glucose behaves like a group of errant sheep, stubbornly refusing to go where the shepherd directs. When that happens, the pancreas pumps out more and more insulin. That's the biochemical equivalent of sending out more and more "shepherds" to get the "sheep" into the "corrals."
Imagine hundreds of shepherds chasing thousands of sheep across a pristine field covered with thick, beautiful green grass. Those hundreds of feet and thousands of hoofs will quickly tear up the field, ripping out or flattening down clumps of grass. Soon, the field that once looked so green and lush will be trampled and scarred, brown and dirty.
Something similar happens inside your body when glucose refuses to move into the storage cells at insulin's command. The interior linings of your arteries, like the grassy field, are "ripped" and "trampled" as the body attempts to overcome this problem.
Eventually, the insulin "shepherds" corral the glucose, and order is restored in the body. But all is not well, for the "field" (the lining of your coronary arteries) is damaged, and there's other damage, as well. This damage sets the stage for heart disease.
We don't know exactly how many hearts have been attacked by Syndrome X, although it may be responsible for as many as 50 percent of all heart attacks - or even more. Unfortunately, very few people are aware of Syndrome X, know whether or not they have it or are doing anything about it. And their doctors aren't telling them
The best way to prevent Syndrome X is to choose your parents carefully. After all, if you have a family history of heart attack, you run a greater risk of having one yourself. But since the wonders of modern biology have yet to give us the option of choosing our parents, we must find a more practical solution.
There are numerous heart attack prevention programs and diets. But none of them gives you the complete and effective approach that attacks all risk factors simultaneously, for none deals with Syndrome X and insulin resistance. In fact, much of their dietary advice makes the syndrome decidedly worse.
Not all cells need insulin in order to absorb blood sugar. Brain cells, for example, do so without the help of the hormone. It's as if evolution realized that getting fuel (glucose) into brain cells was too important a task to depend on the presence of insulin at the right time, in the right amounts. Kidney and red blood cells also "grab" the glucose they need without insulin's assistance. On the other hand, muscle and fat (adipose) cells depend on insulin's aid, and that's where the problems with insulin resistance arise.
Excess insulin in the bloodstream prompts the damage associated with Syndrome X, but the insulin is only trying to do its job. The underlying problem is insulin resistance. About 25 to 30 percent of Americans are resistant to their own insulin - their "shepherds" are simply not strong enough to properly herd glucose. This means that greater amounts of insulin are required to get the job done. Unfortunately, excess insulin is the first in a series of events which triggers the damage to arteries that may precipitate a heart attack.
Insulin resistance is at the heart of Syndrome X. That's why simply lowering total cholesterol or LDL "bad" cholesterol won't solve the problem. And that's why the low-fat, high-carbohydrate diet so highly recommended by most physicians and health organizations is so dangerous for those with the disorder. Remember, carbohydrates become glucose, and glucose must be herded into certain cells. That requires insulin. More carbohydrate equals more glucose equals more insulin: that's the formula for disaster for those with this "unknown" syndrome.
Up until about ten years ago, insulin resistance was recognized as a malady which, if not compensated for, could lead to type 2 diabetes.
Thanks to thirty years' worth of research into Syndrome X, we now know that even if you never develop diabetes, you can still suffer other ill effects from insulin resistance and high insulin levels: you may suffer from a constellation of changes that greatly increases your risk of coronary heart disease. In short, if you are insulin resistant, you are in real trouble.
When to seek Medical Advice:
Assessing Your Own Risk of Heart Disease
Because heart disease and its risk factors can be silent for so long, often with few symptoms until the disease is well underway, it's important to know your personal risk factors. That includes your knowing your family health history and your cholesterol and blood pressure levels.
Two major studies published in the summer of 2003 found that nearly everyone who dies of heart disease, including heart attacks, had at least one or more of the conventional heart disease risk factors: smoking, diabetes, high blood pressure and high cholesterol.
A simple heart disease risk assessment tool based on the Framingham Risk Model can be found online at http://hp2010.nhlbihin.net/atpiii/calculator.asp. It estimates your 10-year risk of having a heart attack or dying of coronary heart disease based on your answers to questions about your personal risk factors. Your risk, whether very high, high, moderate or low, determines what steps you should take to reduce that risk, including whether or not you should be put on medication.
No matter what your age, if you suspect you have heart disease or are at risk of heart disease, talk to your health care professional about diagnostic tests such as an exercise echocardiogram or a nuclear stress test.
Thanks to decades' worth of painstaking study and observation, physicians have compiled a list of the risk factors for heart disease. That list usually looks likes this:
• Elevated LDL "bad" cholesterol
• Low HDL "good" cholesterol
• Elevated blood pressure
• Diabetes mellitus
• Cigarette smoking
• Lack of physical activity
The more of these risk factors you have, the greater your odds of suffering a heart attack.
This standard list of heart disease risk factors is a good start, but it's missing a vital ingredient. The list is inadequate for those with Syndrome X because it does not address insulin resistance or compensatory hyper-insulinemia (excess insulin) and their consequences.
The complete list of heart disease risk factors for people with Syndrome X looks like this:
• Syndrome X risk factors
• Impaired glucose tolerance
• High insulin levels (hyper-insulinemia)
• Elevated triglycerides (blood fats)
• Low HDL "good" cholesterol
• Slow clearance of fat from the blood (exaggerated postprandial lipemia)
• Smaller, more dense LDL "bad" cholesterol particles
• Increased propensity of the blood to form clots
• Decreased ability to dissolve blood clots
• Elevated blood pressure
• Lifestyle factors that worsen Syndrome X
• Lack of physical activity
• The wrong diet
• Cigarette smoking
The additional independent risk factor:
• Higher than normal LDL cholesterol
Notice the differences. The Syndrome X heart disease risk factor list includes the rate at which fat clears from the blood, not just the amount of fat in the blood. It also considers the formation and clearance of blood clots, and the physical characteristics of LDL cholesterol (not just the amount).
Just how important are the Syndrome X risk factors?
Several studies have shown that a low HDL cholesterol, a central feature of Syndrome X, is at least as powerful, if not more so, in increasing risk of heart attack as is high LDL cholesterol. Studies have shown that every separate component of Syndrome X is an individually significant heart attack risk factor. That means that the more components of Syndrome X you have, the greater the heart attack risk. The most reputable research studies reflect this profound fact.
For example, the Quebec Cardiovascular Study found that for each 30 percent elevation in insulin levels, there was a 70 percent increase in risk of heart disease over a five-year period. The risk increased with each added component of Syndrome X.
Conventional Treatment of Syndrome X
Physicians have been concentrating on treating the symptoms of Syndrome X such as hypertension and dyslipidemia rather than concentrating on the underlying problem, which is insulin resistance. Since over 50% of the prescriptions filled in the United States are for hypertension, elevated cholesterol levels, heart disease, and diabetes, you can get a glimpse of the economic importance of this problem.
Syndrome X is usually totally reversible without drugs. The key is to slow down carbohydrate absorption while increasing insulin sensitivity. This can be done by lowering your carbohydrate intake (the low-carb diet), together with a nutritional supplementation program designed to slow carbohydrate absorption, increase insulin sensitivity, and normalize blood sugar levels.
However, human nature (and human metabolism) being what it is, the majority of patients with syndrome X cannot accomplish these goals. In these cases, each metabolic disorder associated with syndrome X needs to be treated individually, and aggressively. A short-term treatment with drugs is seldom but may be needed.
Treating the lipid abnormalities. The lipid abnormalities seen with syndrome X (low HDL, high LDL, and high triglycerides) respond nicely to weight loss and exercise. Treatment should be aimed primarily at reducing LDL and triglyceride levels, and raising HDL levels. Successful drug treatment usually requires treatment with a statin or one of the fibrate drugs, or a combination of a statin with either niacin or a fibrate. It should also be noted that the use of statin drugs is not without its problems.
Treating the clotting disorder. Patients with syndrome X have several disorders of coagulation that make it easier to form blood clots within blood vessels. These blood clots are often a precipitating factor in developing heart attacks. Patients with metabolic syndrome X should generally be placed on daily aspirin therapy to help prevent such clotting events.
Treating the hypertension. High blood pressure is present in more than half the people with metabolic syndrome X, and in the setting of insulin resistance, high blood pressure is especially important as a risk factor. Recent studies have suggested that successfully treating hypertension in patients with diabetes can reduce the risk of death and heart disease substantially. Low dose diuretics should be used according to Dr.Reaven. No more than 12.5 mg of hydrochlorathiazide should be prescribed.
People with Syndrome X should not be prescribed the anti-hypertensive dosages of thiazides that have been recommended in the past. Difficult cases should be controlled with ACE inhibitors. ACE inhibitors increase levels of nitrous oxide (a potent endothelium generated vasodilator), resulting in vasodilatation and blood pressure reduction.
ACE inhibitors also have been shown to improve endothelial function, and so have HMG-CoA reductase inhibitors (such as lovastatin and pravastatin), and to a lesser degree, calcium channel blockers (such as verapamil and nifedipine).
Treating High Blood Sugar. High blood sugar must be normalized. Traditionally there are four points of intervention to reduce blood sugar:
• Pancreas. Two major classes of drugs are the sulonylureas and the meglitinides. Sulfonylureas have been used for more than 4 decades. Their primary goal is to increase the level of endogenous insulin by stimulating the pancreatic secretion. These agents have no direct effect on insulin resistance.
They may decrease the resistance slightly by reducing plasma glucose level. The meglitinide class, of which repaglinide is approved in the U.S., also stimulates insulin release from the pancreas. Clearly, these should be avoided among those with Syndrome X who already have a high insulin level. Further insulin will only worsen the problem.
• Intestines. Alpha-glucosidase inhibitors are currently represented by acabose. The primary mechanism of action of these agents is to inhibit specific enzymes that break down carbohydrates in the small intestine. Absorption of carbohydrates is delayed, resulting in a reduction of postprandial hyperglycemia. No specific action on insulin resistance has been reported.
• Liver. The biguanides, of which metformin is the agent used in the U.S., mainly decrease hepatic glucose production, They also increase peripheral insulin sensitivity, leading to reduced plasma glucose level. They also have some effect in reducing intestinal glucose absorption. Clearly this is a better drug to use than the previous two.
• Muscle. This class of oral agents is known as the thiazolidinediones, of which troglitazone is approved for use in the U.S. It reduces insulin resistance by increasing the uptake of glucose by peripheral tissues such as skeletal tissue. It is therefore uniquely designed to attack insulin resistance.
Self Care strategies for Living with Syndrome X
One in four Americans (25% of our entire nation) are now suffering from Syndrome-X, also called Metabolic Syndrome.
www.americanheart.org says "The metabolic syndrome is characterized by a group of metabolic risk factors in one person. They include:
• Abdominal obesity (excessive fat tissue in and around the abdomen)
• Atherogenic dyslipidemia (blood fat disorders — high triglycerides, low HDL cholesterol and high LDL cholesterol — that foster plaque buildups in artery walls)
• Elevated blood pressure
• Insulin resistance or glucose intolerance (the body can’t properly use insulin or blood sugar)
• Prothrombotic state (e.g., high fibrinogen or plasminogen activator inhibitor–1 in the blood)
• Proinflammatory state (e.g., elevated C-reactive protein in the blood)
People with the metabolic syndrome are at increased risk of coronary heart disease and other diseases related to plaque buildups in artery walls (e.g., stroke and peripheral vascular disease) and type 2 diabetes. The metabolic syndrome has become increasingly common in the United States. It’s estimated that over 50 million Americans have it."
The vast amount of research the Soviet Union did on the extracted active ingredients of Rhodeola Rosea, Aralia Mandshirica, Caucasian Billberry and Georgian Pomengranate show huge positive effects on all of the metabolic risk factors listed above.
Diet change strategies:
Natural Treatment of Syndrome X
While there are no drug treatments that can directly reverse the insulin resistance that causes syndrome X; there is, in fact, a way to reverse the insulin resistance - and that is through diet, exercise, and nutritional supplementation.
Clearly, the following goals should be met in any diet for Syndrome X sufferers:
a. Reduction of carbohydrates. With less carbohydrates around, there will be less insulin needed.
b. Reduction of LDL cholesterol which can lead to heart disease
c. Reduction of blood glucose level
d. Increase in insulin sensitivity
The question is: If you reduce carbohydrate, and reduce fat, then how are you going to get enough calories? If one food group is reduced, the calories must be supplied by another food group. The strategy is clear - reduce carbohydrates, especially simple refined carbohydrates. How you make up the calories is less clear.
There are only two options available: carbohydrates can be replaced with proteins or with fats. Clearly saturated fats should be restricted to reduce the risk of cardiovascular disease and to lower LDL cholesterol level. Therefore, part of the carbohydrate should be replaced with "good" fat.
Replacing carbohydrates with proteins ignores the fact that protein, once in the intestinal tract, converts to amino acid. Amino acids increase insulin secretion. It is unclear, however, whether proteins are as potent as carbohydrates in stimulating insulin secretion
It has been postulated that use of low glycemic-index carbohydrates will avoid worsening the manifestations of Syndrome X due to its slow glucose release and absorption rate. There is little doubt that low glycemic-index carbohydrates such as fruits and vegetables are superior when compared to high glycemic-index carbohydrates such as white flour and white bread.
In a recent paper, substantial increases in the fiber level (exceeding the ADA recommendation) resulted in improved metabolic characteristics, as compared to a high carbohydrate/low fat diet. No comparison was made between the very high fiber diet vs. a diet low in carbohydrates and high in unsaturated fats.
The simplest and most effective approach is to replace the carbohydrates with poly- and mono-unsaturated fats and restrict saturated fat intake, to achieve both lower LDL cholesterol and improve Syndrome X.
2. Nutritional Supplementation.
A variety of natural non-toxic food based compounds can be used. The goals are to normalize blood sugar, and increase insulin sensitivity.
Treating the lipid abnormalities. For Dyslipidemia, the following can be considered: pantethine (300 -1,200 mg), panthothenic acid (300-1,300 mg), guccolipid (50-150 mg), polycosinol (5-10 mg), mineral ascobates (2-5 grams), lysine (2-5 grams), proline (1-2 grams), chromium polynicotinate (400 -1200 mcg), and fish oils (1000 to 4000 mg).
Treating the clotting disorder. To reduce the blood clot risk, natural compounds such as vitamin E (300 to 1200 I.U.) and gingko biloba extracts (30 to 150 mg) have blood thinning properties and help promote circulation. Antioxidant therapy with optimum doses of Vitamin A, C, and E helps to stabilize plaques, improve vascular tone, and reduce thrombus.
Treating the hypertension. To lower blood pressure, antioxidant therapy helps to stabilize plaques and improve vascular tone by inhibiting oxidation of LDL cholesterol.
Treating high blood sugar. For glucose normalization and to increase insulin sensitivity, natural non-toxic compounds that have sugar modulation effects include chromium polynicotinate (400 -1200 mcg), venadyl sulfate (25 -100 mg), lipoic acid (100-300 mg) can be considered.
For rebalancing the internal terrain to enhance digestive balance and efficiency, digestive enzymes, green foods such as chlorella, spirulina, algae, soluble fiber, and probiotics should be considered
For antioxidant deficiency: a strong multi-vitamin with at least 10,000 I.U. of beta carotene, 500 mg of vitamin C, 200mg of selenium, 100 mg of grape seed extract, 30 mg of co-enzyme Q10.
For normalization of adrenal function, pantethine 300-900 mg, pantothenic acid 400-1,200 mg should be considered.
Epidemiological studies have shown that modest exercise is beneficial. However, unequivocal metabolic benefits from exercise will not be achieved from a casual walk a couple of nights a week. Significant, regular, chronic exercise is required to see improvements in insulin action, triglycerides, and HDL cholesterol. Exercise is as powerful a tool as weight loss.
4. Weight Management.
Every attempt should be made to reduce total body weight to within 20% of the "ideal" body weight calculated for age and height. If this is done Syndrome X will improve significantly. There is little question about its effectiveness.
5. Other lifestyle Factors:
a. Alcohol. In population-based studies, moderate drinkers are found to have lower insulin levels as compared to non-drinkers. Our small-scale studies have shown moderate drinkers to be more insulin sensitive. There have been no intervention studies to show that initiating alcohol consumption in individuals who are insulin resistant with low HDL is beneficial. So it is not reasonable to suggest that non-drinkers should start to drink 1-2 drinks per day. On the other hand, we do not have the evidence to recommend abstaining from alcohol.
b. Smoking. Smoking is unequivocally bad, asspciated with high triglycerides, low HDL cholesterol and insulin resistance.
Two of the key factors that affect our health is glucose (also known as blood sugar) and the hormone insulin. Because of the high carbohydrate foods we, as a whole population, now eat, our bodies' levels of glucose and insulin have gone out of control. Such high carbohydrate foods probably include cereals, muffins, breads and rolls, pastas, cookies, donuts, and soft drinks.
Quite simply, we are overdosing on glucose and insulin -- two substances which in high doses will accelerate the aging of our bodies and encourage the onset of diseases. Insulin resistance is the body's way to resist excessive sugar and carbohydrate levels, and 60 million Americans have this problem. When insulin resistance is accompanied by compensatory hyperinsulinemia- (not explained in article), the systemic damage is collectively known as Syndrome X.
Fortunately, Syndrome X can be reversed with dietary, lifestyle, and nutritional supplements and a diet high in unsaturated fat (45%), low in protein (15%), and moderate in carbohydrate (40%). Exercise, weight management, and optimum nutritional supplements such as chromium polynicotinate, vitamin C, proline, lysine, and other antioxidants help to normalize sugar and increase insulin sensitivity.
Vitamin & Nutrient Associations
Even when we try to eat well, we're disadvantaged. The nutritional content of most food has been compromised over the years, not only by deficient soils and modern production, transportation, storage and processing methods, but also by the enormous amounts of chemical and artificial substances added to promote growth, storage life, taste and appearance.
It's for this reason that more and more medical authorities are advocating the use of vitamin and mineral supplements. However, finding them in the right combination can be both confusing and costly.
The nutrition products I am going to recommend you make use of knowledge gained from the botanical world's 6,000 year history. They incorporated health building nutritional herbs with the best modern technology to help our bodies cleanse and detoxify so that the cells - the tiniest living units - can be as fully nourished as possible. This allows the cells to grow, repair and to perform their functions with the best possible efficiency so that we feel and look better and are more able to prevent and fight disease. Once the body begins to clear itself of toxins it can more efficiently absorb nutrition.
Further reading through our articles on health issues will give you a body of information that will help you decide what options you have to deal with the underlying causes of your problem through giving your body the nutrition products that will assist you body to heal from the inside out.
We wish you well in your search for solutions to this problem and your movement towards better health in all areas.
More Resources available about Syndrome X :
For the latest anti-aging related health issues, visit Dr. Lam at www.LamMD.com.
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Diet Tips for Metabolic Syndrome X
When you are diagnosed with metabolic syndrome, your health care professional will likely prescribe some lifestyle changes. They may also prescribe medication …
Syndrome X also referred to as Metabolic syndrome is not a disease in itself but rather encompasses a range of conditions that often occur together.
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